{"id":2386,"date":"2018-12-15T21:13:28","date_gmt":"2018-12-15T12:13:28","guid":{"rendered":"http:\/\/spera.rdy.jp\/?page_id=2386"},"modified":"2020-12-08T10:34:58","modified_gmt":"2020-12-08T01:34:58","slug":"development-stage","status":"publish","type":"page","link":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/en\/technology\/drug\/development-stage\/","title":{"rendered":"API process development depending on each development stage"},"content":{"rendered":"<p>SPERA PHARMA develops and proposes API manufacturing process satisfying customer\u2019s needs.<\/p>\n<p>Goals for process R&#038;D depend on the development stages and situations for development programs. In general, while the speed to support development timeline is  highly required in an early  development stage, the robustness and R&#038;D cost saving are considered in a  middle stage, and  then  the  competitiveness of commercial cost and the high-level process control strategies need to be established in a late stage.<\/p>\n<p>By designing API synthetic route based on the structure-activity relationship, the containment process for the highly potent  compound  has  been minimized. The achievement  provides us with flexible manufacturing, saving costs\/time, reducing workload, and environmental friendly process. (Tetrahedron, 2013, 69, 8564)<\/p>\n<p><a href=\"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-content\/uploads\/2019\/02\/02en.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-content\/uploads\/2019\/02\/02en.jpg\" alt=\"Process R&amp;D example; API-cost saving\" width=\"570\" height=\"602\" class=\"alignnone size-full wp-image-4399\" srcset=\"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-content\/uploads\/2019\/02\/02en.jpg 570w, https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-content\/uploads\/2019\/02\/02en-284x300.jpg 284w, https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-content\/uploads\/2019\/02\/02en-151x160.jpg 151w\" sizes=\"(max-width: 570px) 100vw, 570px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SPERA PHARMA develops and proposes API manufacturing process satisfying customer\u2019s needs. Goals for process R&#038; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":2327,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_locale":"en_US","_original_post":"676","footnotes":""},"class_list":["post-2386","page","type-page","status-publish","hentry","en-US"],"acf":[],"_links":{"self":[{"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/pages\/2386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/comments?post=2386"}],"version-history":[{"count":2,"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/pages\/2386\/revisions"}],"predecessor-version":[{"id":7264,"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/pages\/2386\/revisions\/7264"}],"up":[{"embeddable":true,"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/pages\/2327"}],"wp:attachment":[{"href":"https:\/\/heuristic-ardinghelli.153-122-123-210.plesk.page\/wp-json\/wp\/v2\/media?parent=2386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}